Description
Targeted therapy is a therapeutic method of inhibiting specific cell metabolic pathways. The prerequisite for successful targeted treatment is the definition of the correct “molecular target” and the selection of the right active substance against the specified “target “,
The key issue in selecting targeted therapy is proper diagnosis and consideration of individual differences that determine the success of the therapeutic used .
Each of us dreams of a miracle pill for all the world’s diseases, unfortunately, such a pill does not exist ( Except for BPC-157). When it comes to the topic of hair growth, it is very complicated, mainly due to the initial condition of the individual. Unfortunately, often with severely damaged hair follicles, there can only be a cosmetic effect. For advanced cases, a stack of several peptides and micro-needling is often needed. It is further a cheaper alternative compared to hair transplantation.
PTD-DBM is a topical peptide for hair. It interacts with the canonical WNT signaling scales(The term Wnt was coined from a combination of the names of genes learned in the fruit fly(wingless) and humans(int-1) . Wnt proteins are a group of conserved secretory proteins that interact closely with extracellular matrix glycosaminoglycans- The Wnt pathway is involved in stem cell homeostasis, among other things. colon, bones, blood and even hair. ) to protect hair follicles by inhibiting the CXXC5 protein. CXXC5 causes hair loss through negative regulation of the WNT pathway and inhibits collagen production in vitro. This pathway involves a cascade of protein signals that carry PTD-DBM effects throughout the body to regulate cell growth and signaling. The WNT / β-catenin pathway plays a key role in hair regeneration through wound healing and collagen deposition. PTD-DBM disrupts the CXXC5-DVL interaction, thereby activating the WNT pathway. This WNT pathway has been proven to help rescue DHT-induced hair follicle miniaturization.
Studies have shown that PTD-DBM induces hair neogenesis much more effectively when combined with valproic acid, which stimulates the Wnt / β-catenin pathway when applied topically.
This pathway has been proven to help rescue the miniaturization of hair follicles caused by DHT.
- Synergistic action with other peptides
- Regulates the differentiation of hair follicles
- Improved hair growth.
- Increased hair growth.
- Inhibition of hair follicle shrinkage to prevent hair loss
- Works best with micro-needling
- Induces collagen growth
- Induction of fibroblast migration
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