{"id":2929,"date":"2026-04-13T11:38:49","date_gmt":"2026-04-13T09:38:49","guid":{"rendered":"http:\/\/lunapharm.co\/?post_type=product&p=2929"},"modified":"2026-05-18T17:50:27","modified_gmt":"2026-05-18T15:50:27","slug":"frag-176-191-5mg","status":"publish","type":"product","link":"https:\/\/lunapharm.co\/en\/product\/frag-176-191-5mg\/","title":{"rendered":"FRAG 176-191 5mg"},"content":{"rendered":"

Czym<\/span> jest<\/span> FRAG<\/span> 176-191?<\/span><\/h3>\n

FRAG<\/span> 176-191<\/span> (cz\u0119sto<\/span> opisywany<\/span> te\u017c<\/span> jako<\/span> hGH<\/span> Fragment<\/span> 176\u2013191<\/span><\/span>;<\/span> w<\/span> cz\u0119\u015bci<\/span> bada\u0144<\/span> jako<\/span> pochodne<\/span> typu<\/span> AOD<\/span><\/span>)<\/span> to<\/span> kr\u00f3tki<\/span> peptyd<\/span> wywodz\u0105cy<\/span> si\u0119<\/span> z<\/span> C-ko\u0144cowego<\/span> fragmentu<\/span> hormonu<\/span> wzrostu.<\/span> Zainteresowanie<\/span> tym<\/span> fragmentem<\/span> wynika<\/span> z<\/span> obserwacji,<\/span> \u017ce<\/span> mo\u017ce<\/span> on<\/span> wykazywa\u0107<\/span> bardziej<\/span> \u201eukierunkowany\u201d<\/span> profil<\/span> dzia\u0142ania<\/span> na<\/span> tkank\u0119<\/span> t\u0142uszczow\u0105<\/span> ni\u017c<\/span> pe\u0142na<\/span> cz\u0105steczka<\/span> hGH.<\/span><\/p>\n

Jak<\/span> dzia\u0142a<\/span> w<\/span> organizmie<\/span> (mechanizm<\/span> \u2013<\/span> uj\u0119cie<\/span> praktyczne)<\/span><\/h3>\n

W<\/span> literaturze<\/span> naukowej<\/span> ten<\/span> fragment<\/span> wi\u0105\u017ce<\/span> si\u0119<\/span> przede<\/span> wszystkim<\/span> z<\/span> modulacj\u0105<\/span> przemian<\/span> lipid\u00f3w<\/span> w<\/span> adipocytach<\/span> (kom\u00f3rkach<\/span> t\u0142uszczowych):<\/span><\/p>\n

    \n
  • Wspieranie<\/span> lipolizy:<\/span><\/span> mo\u017ce<\/span> sprzyja\u0107<\/span> uwalnianiu<\/span> kwas\u00f3w<\/span> t\u0142uszczowych<\/span> z<\/span> tr\u00f3jgliceryd\u00f3w<\/span> magazynowanych<\/span>w<\/span> tkance<\/span> t\u0142uszczowej.<\/span><\/li>\n
  • Ograniczanie<\/span> lipogenezy:<\/span><\/span> w<\/span> modelach<\/span> badawczych<\/span> obserwowano<\/span> obni\u017cenie<\/span> proces\u00f3w<\/span> \u201etworzenia\u201d<\/span> i<\/span>odk\u0142adania<\/span> t\u0142uszczu<\/span> w<\/span> adipocytach.<\/span><\/li>\n
  • Wp\u0142yw<\/span> na<\/span> wydatek<\/span> energetyczny:<\/span><\/span> w<\/span> badaniach<\/span> przedklinicznych<\/span> opisywano<\/span> zwi\u0119kszenie<\/span> marker\u00f3w<\/span>utleniania<\/span> t\u0142uszczu<\/span> i\/lub<\/span> wydatku<\/span> energetycznego.<\/span><\/li>\n<\/ul>\n

    W<\/span> skr\u00f3cie:<\/span> FRAG<\/span> 176-191<\/span> jest<\/span> kojarzony<\/span> z<\/span> przesuni\u0119ciem<\/span> r\u00f3wnowagi<\/span> w<\/span> tkance<\/span> t\u0142uszczowej<\/span> w<\/span> stron\u0119<\/span> spalania\/uwalniania<\/span><\/span> zamiast<\/span> magazynowania<\/span><\/span>.<\/span><\/p>\n

    Potencjalne<\/span> w\u0142a\u015bciwo\u015bci<\/span> (na<\/span> podstawie<\/span> bada\u0144)<\/span><\/h3>\n

    Najcz\u0119\u015bciej<\/span> opisywane<\/span> kierunki<\/span> dzia\u0142ania<\/span> w<\/span> badaniach:<\/span><\/p>\n

      \n
    • wsparcie<\/span> redukcji<\/span> przyrostu<\/span> masy<\/span> cia\u0142a<\/span><\/span> w<\/span> modelach<\/span> oty\u0142o\u015bci<\/span> (bez<\/span> istotnej<\/span> zmiany<\/span> spo\u017cycia<\/span> pokarmu<\/span> w<\/span>cz\u0119\u015bci<\/span> modeli),<\/span><\/li>\n
    • poprawa<\/span> profilu<\/span> przemian<\/span> t\u0142uszcz\u00f3w<\/span> w<\/span> tkance<\/span> t\u0142uszczowej<\/span> (<\/span>\u2191<\/span> lipoliza,<\/span> \u2193<\/span> lipogeneza<\/span><\/span>),<\/span><\/li>\n
    • mo\u017cliwe<\/span> wsparcie<\/span> utleniania<\/span> t\u0142uszcz\u00f3w<\/span><\/span> (fat<\/span> oxidation)<\/span> i<\/span> produkcji<\/span> energii<\/span> z<\/span> lipid\u00f3w.<\/span><\/li>\n<\/ul>\n

      Co<\/span> odr\u00f3\u017cnia<\/span> go<\/span> od<\/span> pe\u0142nego<\/span> hormonu<\/span> wzrostu?<\/span><\/h3>\n

      To<\/span> fragment<\/span><\/span> hGH,<\/span> wi\u0119c<\/span> jego<\/span> profil<\/span> badawczy<\/span> bywa<\/span> opisywany<\/span> jako<\/span> bardziej<\/span> skoncentrowany<\/span> na<\/span> tkance<\/span> t\u0142uszczowej.<\/span> Jednocze\u015bnie<\/span> mechanizm<\/span> i<\/span> \u201eselektywno\u015b\u0107\u201d<\/span> nie<\/span> s\u0105<\/span> w<\/span> pe\u0142ni<\/span> jednoznaczne<\/span> \u2014<\/span> wnioski<\/span> zale\u017c\u0105<\/span> od<\/span> modelu<\/span> (in<\/span> vitro\/zwierz\u0119ta)<\/span> i<\/span> protoko\u0142u<\/span> badania.<\/span><\/p>\n

       <\/p>\n

      Produkt przeznaczony wy\u0142\u0105cznie do bada\u0144 laboratoryjnych (Research Use Only). Nie jest lekiem, suplementem diety ani wyrobem medycznym. Nie jest przeznaczony do stosowania u ludzi ani zwierz\u0105t, w tym do spo\u017cycia, inhalacji, iniekcji, aplikacji na sk\u00f3r\u0119 lub w jakiejkolwiek innej formie u\u017cycia biologicznego. Nie wolno go podawa\u0107 osobom trzecim ani wykorzystywa\u0107 w celach terapeutycznych, diagnostycznych lub weterynaryjnych. U\u017cywa\u0107 wy\u0142\u0105cznie w warunkach laboratoryjnych przez wykwalifikowany personel, zgodnie z obowi\u0105zuj\u0105cymi procedurami bezpiecze\u0144stwa. Produkt nie nadaje si\u0119 do spo\u017cycia przez ludzi i jest wy\u0142\u0105cznie do cel\u00f3w badawczych.<\/strong><\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

      FRAG 176-191<\/span> to syntetyczny fragment ludzkiego hormonu wzrostu (ko\u0144cowe aminokwasy 176\u2013191), badany g\u0142\u00f3wnie pod k\u0105tem wp\u0142ywu na metabolizm tkanki t\u0142uszczowej \u2014 nasilanie lipolizy<\/span> i hamowanie lipogenezy<\/span>.<\/strong><\/p>","protected":false},"featured_media":2930,"comment_status":"open","ping_status":"closed","template":"","meta":{"_bst_post_transparent":"default","_bst_post_title":"","_bst_post_layout":"default","_bst_post_sidebar_id":"","_bst_post_content_style":"default","_bst_post_vertical_padding":"default","_bst_post_feature":"","_bst_post_feature_position":"","_bst_post_header":false,"_bst_post_footer":false},"product_brand":[],"product_cat":[52],"product_tag":[],"class_list":["post-2929","product","type-product","status-publish","has-post-thumbnail","product_cat-peptydy","first","instock","sale","shipping-taxable","purchasable","product-type-simple","entry","content-bg","loop-entry"],"_links":{"self":[{"href":"https:\/\/lunapharm.co\/en\/wp-json\/wp\/v2\/product\/2929","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lunapharm.co\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/lunapharm.co\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/lunapharm.co\/en\/wp-json\/wp\/v2\/comments?post=2929"}],"version-history":[{"count":4,"href":"https:\/\/lunapharm.co\/en\/wp-json\/wp\/v2\/product\/2929\/revisions"}],"predecessor-version":[{"id":2937,"href":"https:\/\/lunapharm.co\/en\/wp-json\/wp\/v2\/product\/2929\/revisions\/2937"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/lunapharm.co\/en\/wp-json\/wp\/v2\/media\/2930"}],"wp:attachment":[{"href":"https:\/\/lunapharm.co\/en\/wp-json\/wp\/v2\/media?parent=2929"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/lunapharm.co\/en\/wp-json\/wp\/v2\/product_brand?post=2929"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/lunapharm.co\/en\/wp-json\/wp\/v2\/product_cat?post=2929"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/lunapharm.co\/en\/wp-json\/wp\/v2\/product_tag?post=2929"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}