In plasma we can find different isoforms and fragments of hGH . Studies of specific domains and fractions of the protein have revealed that they can be attributed to different actions of the protein: in vitro and in vivo experiments have shown that several fragments of the N-terminal region of hGH, namely 1-15, 1-42, 6-13 and 32-46 show insulin-enhancing effects . The hGH 108-129 region was found to induce high mitogenic responses , while the carboxyl end of hGH 171-191 appeared to be a lipid mobilizing domain that inhibits acetyl-CoA carboxylase activity in adipocytes and hepatocytes.
The 176-191 growth hormone peptide fragment, also known as the HGH 176-191 fragment, is a modified amino acid 176-191 form of the GH polypeptide. This region, consisting of amino acids 176-191, accounts for less than 10% of the total size of the GH molecule and has no effect on IGF-1 elevation due to its lack of connection to the GH receptor. Frag helps in fat metabolism and inhibits the formation of fatty acids and other lipids in the body. Ergo, it directly affects adipose tissue, enhancing the lipolytic effect. This makes fat metabolism faster and more powerful than HGH, so Fragment
176-191 appears to be j suitable option in burning body fat and dealing with obesity than regular human growth hormone.
THE POSSIBLE BENEFITS OF THE HGH FRAGMENT HAVE BEEN SCIENTIFICALLY INVESTIGATED
* Powerful fat burning properties without side effects.
* Stimulates lipolysis and inhibits lipogenesis.
* Does not cause changes in glucose levels and tolerance, insulin sensitivity or IGF-1 levels.
* HGH fragment can be up to 12.5 times more potent than HGH for fat burning.
* Is a more suitable option for burning fat and treating obesity than the usual hormone.
* Increases energy levels.
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